By Derek LeRoith
Quantity 2 has inquisitive about features of the pituitary gland either anterior (growth hormone and prolactin receptors, and GH motion) and posterior (vasopressin) pituitary. moreover, thyroid melanoma and steroidogenic enzymes and precocious puberty are lined. ultimately, the "hot themes" comprise leptin and development issue signaling.
Read or Download Advances in Molecular and Cellular Endocrinology, Vol. 2 PDF
Similar endocrinology books
Written by means of a multidisciplinary crew of specialists enthusiastic about the advance of criteria and instructions for its administration within the united states, united kingdom, Europe and Asia, the booklet comprises succinct and an expert summaries of the administration of thyroid melanoma. each bankruptcy describes a special element of care, and offers transparent and distinct information regarding taking care of sufferers with this staff of tumors.
Fluid problems play a task in approximately each patient's presentation and will occasionally be the major to knowing an doubtful or tricky case. This detailed source truly and comprehensively describes the normal chinese language drugs view of the body structure and pathology of fluids in the physique. Covers problems of sweating and urination, edema, irregular lacrimation, skinny mucus syndrome, and prerequisites of over the top phlegm and dampness within the physique, resembling bronchial asthma, digestive difficulties, arthritis, epilepsy, and convulsions.
Within the Diabetic Foot: clinical and Surgical administration, a exotic panel of clinicians-many training on the recognized Joslin-Beth Israel Deaconess Foot Center-illuminate the winning new multidisciplinary procedure now basically required for the profitable remedy of this clinical challenge. Drawing at the stories of diabetologists, podiatrists, vascular surgeons, infectious illness experts, orthotists, plastic and orthopedic surgeons, the e-book truly describes verified suggestions recognized to be potent.
This publication on abnormalities in puberty provides an outline at the most recent wisdom at the mechanisms of the developmental tactics of puberty. even supposing the precise mechanisms of reawakening of the GnRH pulse generator on the onset of puberty nonetheless need to be elucidated, many genetic and environmental elements were pointed out to play an enormous position.
- Understanding Kidney Diseases
- Computational Intelligence in Medical Informatics
- Early Diagnosis and Treatment of Endocrine Disorders (Contemporary Endocrinology)
- Sourcebook of Models for Biomedical Research
- Fluid Physiology and Pathology in Traditional Chinese Medicine, 2e
- Diabetes Research: A Guide for Postgraduates
Extra resources for Advances in Molecular and Cellular Endocrinology, Vol. 2
1989). GH-R mRNA expression in rats is low at birth, but rises sharply at two to three weeks of age, reaching a plateau several weeks later. In chickens, hepatic GH-R mRNA appears on embryonic day 15, peaks by days 17-19, and declines on day 21, the day of hatching (Burnside and Cogburn, 1992). Approximately two weeks after birth, chicken hepatic GH-R mRNA levels begin to increase again, reaching a peak as the animal reaches mature body weight. The cloned prolactin receptor (PRL-R) is -30% identical to the GH-R, and both receptors are members of the cytokine receptor superfamily 38 MICHAEL I.
1994). Therefore, different segments of the intracellular region of the GH-R may be required for phosphorylation of different proteins. , 1995). , 1992; Winston and Bertics, 1992). , 1993). , 1994). , 1994). Figure 1 summarizes the structure-function studies discussed in this section. , 1994). Subsequently, different cytokine receptors were found to activate various STATs in response to ligand binding. To date, six STATs have been characterized and cloned (Ihle, 1996). These proteins comprise a related family that share --28 to 40% sequence identity in the first -700 amino acids, but differ widely at the COOH-terminus.
Rev. 12, 235-251. A. (1996). Characterization oflactogen receptor binding site 1 of human prolactin. J. Biol. Chem. 271, 14353-14360. , & Akira, S. (1994). Cytokine signal transduction. Cell 76, 253-262. , & Miyajima, A. (1994). Multimeric cytokine receptors. Trends Endocrinol. Metab. 5, 8-14. M. (1994). Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors. Protein Sci. 3, 1697-1705. A. (1994). Prolactin induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase.
Advances in Molecular and Cellular Endocrinology, Vol. 2 by Derek LeRoith