Andrew D Shaw; et al's Acute care of the cancer patient PDF

By Andrew D Shaw; et al

ISBN-10: 0824726898

ISBN-13: 9780824726898

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14. Fidler IJ. Experimental orthotopic models of organspecific metastasis by human neoplasms. Adv Mol Cell Biol 1994; 9:191–215. 15. Price JE. Host–tumor interaction in progression of breast cancer metastasis. In Vivo 1994; 8:145–154. 16. Hart IR. ‘‘Seed and soil’’ revisited: mechanisms of site-specific metastasis. Cancer Metastasis Rev 1982; 1: 5–16. 17. Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977; 197:893–895. 18. Fidler IJ, Ellis LM.

Takahasi Y, Mai M, Wilson MR, Ellis LM. Sitedependent expression of vascular endothelial growth factor, angiogenesis and proliferation in human gastric carcinoma. Int J Oncol 1996; 8:701–705. 58. Sloane BF, Honn KV. Cysteine proteinase and metastasis. Cancer Metastasis Rev 1984; 3:249–265. 59. Jones PA, DeClerck YA. Extracellular matrix destruction by invasive tumor cells. Cancer Metastasis Rev 1982; 1:289–319. 60. Liotta LA, Rao CN, Barksy SH. Tumor invasion and the extracellular matrix. Lab Invest 1983; 49:636–649.

Heterogeneity of blood vessel distribution in surgical specimens of human cancers is well documented (50,51). Benign neoplasms are sparely vascularized and tend to grow slowly in contrast to highly vascularized and rapidly growing malignant tumors (51). However, the distribution of vessels in a tumor is not uniform, and Weidner et al. , tumors exhibit intralesional and zonal heterogeneity for MVD. Similarly, the expression of proangiogenic molecules in surgical specimens of human colon carcinoma was determined by in situ hybridization technique.

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Acute care of the cancer patient by Andrew D Shaw; et al

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